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With the current opioid crisis in the US, finding new non-addictive painkillers and other relief methods is key. An experimental, non-opioid drug known as EMA is showing promise, and now researchers at Washington University in St Louis have found that it works by targeting a different part of the body, outside of the nervous system. After about 64, opioid-overdose deaths in , the Department of Health and Human Services declared a public health emergency , and a key part of dealing with the issue is the development of new treatments and drugs. Some of these include snail venom , green light , ultrasound-triggered nerve blockers , and even marijuana , while other teams are experimenting with exploiting the brain's natural pain relief methods, blocking the pathways that lead to addiction, or disrupting pain-signaling proteins. Recently, the experimental drug EMA has been shown to be an effective painkiller, particularly for lingering pain after a bout of shingles.